Selective separations and hydrodynamic studies: a new approach using molecularly imprinted nanosphere composite membranes

A new approach of selective membrane-based separation has been developed by coating molecularly imprinted nanoparticles onto the surface of a membrane disc whereby a selective composite membrane shall be realized. The imprints at the surface of the nanoparticles are comparable to footprints of specific molecules. These molecules are present during the synthesis of the particles and serve as a molecular template, thus imprinting their shape in the forming particle. The selectivity of the nanoparticles was shown in particle suspension using an enantiomeric model template. The permeability and porosity of the nanoparticle layer were determined by experiments for investigation of feasibility under hydrodynamic aspects. The Carman–Kozeny equation was modified and validated as an applicable theoretical model. The combination of a cost-efficient membrane disc as support for an selective nanoparticle layer can provide an efficient way in purification and sensing processes.

gP : DP Membrane surface, m2 Membrane diameter, m Particle diameter, m Height of particle layer, m Mass of particle layer, g Pressure loss, bar Membrane resistance, m!1 Particle layer resistance, m!1 Volume specific surface, m2/m3 Medial flow velocity, m/s Volume flow, m3/s — — — — Volume porosity of particle layer Loop way factor, =25/12 Viscosity, kg/s/m Density of nanoparticle, kg/m3 Greek Nanoparticles composed of poly(MAA-coEGDMA) were synthesized by mini-emulsion polymerization allowing direct non-covalent imprinting of a chiral amino acid derivative. The — — — — — — — — — — —